HPLC

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Nacalai USA provides Cosmosil brand HPLC columns. The Cosmosil chromatography product line includes several robust reversed phase and prep columns as well as specialty columns such as the Cholester (cholesteryl group), NPE (nitrophenylethyl group), PYE (pyrenylethyl group) and Sugar-D. Cosmosil Buckyprep (pyrenylpropyl group) and PBB (pentabromobenzyl group) columns are well recognized worldwide for Fullerene separation.

Our product are showed as follow:

Core-Shell Columns

1. COSMOCORE 2.6C18

  • 2.6 µm Core Shell Particle
  • Increased loading capacity
  • Excellent pH stability (1.5-10)

 

Analytical Column (Particle size : 2.6 µm) COSMOCORE 2.6C18

Product Name Size Product No.
COSMOCORE 2.6C18 2.1 mm I.D. x 30 mm 12632-31
2.1 mm I.D. x 50 mm 12631-41
2.1 mm I.D. x 75 mm 12630-51
2.1 mm I.D. x 100 mm 12614-71
2.1 mm I.D. x 150 mm 12612-91
3.0 mm I.D. x 30 mm 12611-01
3.0 mm I.D. x 50 mm  12609-51
 3.0 mm I.D. x 75 mm 12608-61
 3.0 mm I.D. x 100 mm 12607-71
 3.0 mm I.D. x 150 mm 12602-21
 4.6 mm I.D. x 30 mm 12601-31
4.6 mm I.D. x 50 mm  12600-41
 4.6 mm I.D. x 75 mm 12599-91
4.6 mm I.D. x 100 mm  12598-01
 4.6 mm I.D. x 150 mm 12597-11
4.6 mm I.D. x 250 mm  12596-21

2. COSMOCORE 2.6Cholester

  • Cholesterol-bonded reversed-phase core-shell column
  • Usable under the same conditions as C18 columns
  • Better selectivity for cis-trans isomers, polyphenols, and natural products

 

Analytical Column (Particle size : 2.6 µm) COSMOCORE 2.6 Cholester Column

Product Name Size Product No.
COSMOCORE 2.6Cholester 2.1 mm I.D. x 30 mm 12858-91
2.1 mm I.D. x 50 mm 12859-81
2.1 mm I.D. x 75 mm 12860-41
2.1 mm I.D. x 100 mm 12861-31
2.1 mm I.D. x 150 mm 12862-21
3.0 mm I.D. x 30 mm 12863-11
3.0 mm I.D. x 50 mm  12864-01
 3.0 mm I.D. x 75 mm 12866-81
 3.0 mm I.D. x 100 mm 12867-71
 3.0 mm I.D. x 150 mm 12868-61
 4.6 mm I.D. x 30 mm 12869-51
4.6 mm I.D. x 50 mm  12870-11
 4.6 mm I.D. x 75 mm 12871-01
4.6 mm I.D. x 100 mm  12872-91
 4.6 mm I.D. x 150 mm 12873-81
4.6 mm I.D. x 250 mm  12875-61

3. COSMOCORE 2.6PBr

  • Separate hydrophilic compounds in reversed-phase conditions
  • Retain hydrophilic compounds longer than C18
  • Greater sample loading capacity than HILIC
  • High performance similar to sub-2 µm particles with lower back pressure

Suitable Samples

  • Hydrophilic compounds
  • Nucleic acids and derivatives
  • Surfactants
  • Glycosides
  • Peptides

 

Analytical Column (Particle size : 2.6 µm) COSMOCORE 2.6PBr Column

Product Name Size Product No.
COSMOCORE 2.6PBr 2.1 mm I.D. x 30 mm 13692-21
2.1 mm I.D. x 50 mm 13693-11
2.1 mm I.D. x 75 mm 13694-01
2.1 mm I.D. x 100 mm 13695-91
2.1 mm I.D. x 150 mm 13697-71
3.0 mm I.D. x 30 mm 13698-61
3.0 mm I.D. x 50 mm  13699-51
 3.0 mm I.D. x 75 mm 13700-01
 3.0 mm I.D. x 100 mm 13701-91
 3.0 mm I.D. x 150 mm 13703-71
 4.6 mm I.D. x 30 mm 13705-51
4.6 mm I.D. x 50 mm  13712-51
 4.6 mm I.D. x 75 mm 13714-31
4.6 mm I.D. x 100 mm  13715-21
 4.6 mm I.D. x 150 mm 13719-81
4.6 mm I.D. x 250 mm  13734-71

Other sizes may be available.

UHPLC-compatible prefilter

Product Name Product No. In Out Description   PKG Size
U-Fil UHPLC-compatible prefilter 12571-31 UHPLC UHPLC Filter: 0.5 µm
Tubing connecting diameter: 1/16 
1 PKG
12572-21 HPLC UHPLC 1 PKG
U-Fil replacement filter 28150  -  -  Filter: 0.5 µm, Material: SUS316L  5 PKG/ Pack

HPLC Column

1. COSMOSIL 5C18-MS-II

  • Multi-purpose C18 Column
  • High reproducibility
  • A wide range of applications
Product Name Size Product No.
COSMOSIL 5C18-MS-II Guard Column/Guard Cartridge
4.6 mm I.D. x 10 mm 38014-31
4.6 mm I.D. x 10 mm Cartridge 38015-89
10 mm I.D. x 20 mm 38016-11
20 mm I.D. x 20 mm 05790-81
20 mm I.D. x 50 mm 34371-71
28 mm I.D. x 50 mm 34347-01
COSMOSIL 5C18-MS-II Packed Column
1.0 mm I.D. x 50 mm 02824-31
1.0 mm I.D. x 150 mm 02896-01
2.0 mm I.D. x 30 mm 05876-71
2.0 mm I.D. x 50 mm 04355-21
2.0 mm I.D. x 100 mm 05597-31
2.0 mm I.D. x 150 mm 38025-91
2.0 mm I.D. x 250 mm 05761-61
3.0mmI.D. x 100mm 05458-51
3.0 mm I.D. x 150 mm 34245-31
3.0 mm I.D. x 250 mm 34254-11
4.6 mm I.D. x 30 mm 34341-61
4.6 mm I.D. x 50 mm 38017-01
4.6 mm I.D. x 100 mm 38018-91
4.6 mm I.D. x 150 mm 38019-81
4.6 mm I.D. x 250 mm 38020-41
6.0 mm I.D. x 150 mm 38021-31
6.0 mm I.D. x 250 mm 38022-21
10 mm I.D. x 50 mm 05789-21
10 mm I.D. x 150 mm 34355-91
10 mm I.D. x 250 mm 38023-11
20 mm I.D. x 150 mm 05091-41
20 mm I.D. x 250 mm 38024-01
28 mm I.D. x 250 mm 05760-71

 

2. COSMOSIL 3C18-EB

  • Excellent for Basic compounds
  • Suitable for Drug Analysis
Product Name Size Product No.
COSMOSIL 3C18-EB Guard Column 4.6 mm I.D. x 10 mm 09839-41
COSMOSIL 3C18-EB
Guard Cartridge (2 PKG)** 
2.0 mm I.D. x 10 mm 11892-74
4.6 mm I.D. x 10 mm  11890-94
COSMOSIL 3C18-EB Packed Column 2.0 mm I.D. x 50 mm 09794-21
2.0 mm I.D. x 75 mm 09795-11
2.0 mm I.D. x 100 mm 09796-01
2.0 mm I.D. x 150 mm 09797-91
2.0 mm I.D. x 250 mm 09798-81
3.0 mm I.D. x 50 mm 09799-71
3.0 mm I.D. x 75 mm 09800-21
3.0 mm I.D. x 100 mm 09811-81
3.0 mm I.D. x 150 mm 09814-51
3.0 mm I.D. x 250 mm 09827-91
4.6 mm I.D. x 50 mm 09840-01
4.6 mm I.D. x 75 mm* 09841-91
4.6 mm I.D. x 100 mm* 09842-81
4.6 mm I.D. x 150 mm* 09843-71
4.6 mm I.D. x 250 mm 09844-61

 

3. COSMOSIL 5C18-AR-II

  • Features strong acid resistance
  • Suitable for acid compounds and peptides

Analytical Column (Particle Size : 5 µm) COSMOSIL 5C18-AR-II

Product Name Size Product No.
COSMOSIL 5C18-AR-II Guard Column/Guard Cartridge
4.6 mm I.D. x 10 mm 38141-61
4.6 mm I.D. x 10 mm Cartridge 38008-89
10 mm I.D. x 20 mm 38148-91
20 mm I.D. x 20 mm 34458-51
20 mm I.D. x 50 mm 34479-81
28 mm I.D. x 50 mm 34363-81
COSMOSIL 5C18-AR-II Packed Column
1.0 mm I.D. x 50 mm 02955-21
1.0 mm I.D. x 150 mm 02951-61
2.0 mm I.D. x 30 mm 05098-71
2.0 m m I.D. x 50 mm 34400-81
2.0 mm I.D. x 100 mm 34469-11
2.0 mm I.D. x 150 mm 37992-51
2.0 mm I.D. x 250 mm 05272-71
3.0 mm I.D. x 100 mm 05791-71
3.0 mm I.D. x 150 mm 38028-61
3.0 mm I.D. x 250 mm 38029-51
4.6 mm I.D. x 30 mm 05877-61
4.6 mm I.D. x 50 mm 38142-51
4.6 mm I.D. x 100 mm 38143-41
4.6 mm I.D. x 150 mm 38144-31
4.6 mm I.D. x 250 mm 38145-21
6.0 mm I.D. x 150 mm 38146-11
6.0 mm I.D. x 250 mm 38147-01
10 mm I.D. x 50 mm 05369-21
10 mm I.D. x 150 mm 34350-41
10 mm I.D. x 250 mm 38149-81
20 mm I.D. x 150 mm 34316-01
20 mm I.D. x 250 mm 38150-41
28 mm I.D. x 250 mm 34362-91

4.6 mm I.D. x 10 mm Cartrige contains 3 PKG. Cartridge Holder (Product number: 38009-79) is required.

 

Preparative Column (Particle Size : 15 µm) COSMOSIL 15C18-AR-II

Product Name Size Product No.
COSMOSIL 15C18-AR-II Guard Column
28 mml.D. x 50 mm 38030-11
50 mml.D. x 50 mm 38057-81
COSMOSIL 15C18-AR-II Packed Column
28 mml.D. x 250 mm 37978-51
50 mml.D. x 250 mm 38058-71
50 mml.D. x 500 mm 05884-61

Fast LC Column (Particle Size : 3µm) COSMOSIL 3C18-AR-II

Product Name Size Product No.
COSMOSIL 3C18-AR-II Packed Column
2.0 mm l.D. x 50 mm 05478-91
4.6 mm l.D. x 10 mm 38068-41
4.6 mm l.D. x 50 mm 38069-31
4.6 mm l.D. x 100 mm 38070-91

 

4. COSMOSIL 5C18-PAQ

  • Compatible with 100% water based mobile phase
  • Suitable for hydrophilic compounds

Analytical Column (Particle Size : 5 µm) COSMOSIL 5C18-PAQ

Product Name Size Product No.
COSMOSIL 5C18-PAQ Guard Column
4.6 mm I.D. x 10 mm 02484-91
10 mm I.D. x 20 mm 34457-61
20 mm I.D. x 20 mm 05803-11
20 mm I.D. x 50 mm 05804-01
28 mm I.D. x 50 mm 34455-81
COSMOSIL 5C18-PAQ Packed Column
1.0 mm I.D. x 50 mm 05792-61
1.0 mm I.D. x 150 mm 05793-51
2.0 mm I.D. x 30 mm 05878-51
2.0 mm I.D. x 50 mm 05794-41
2.0 mm I.D. x 100 mm 05470-71
2.0 mm I.D. x 150 mm 34449-71
2.0 mm I.D. x 250 mm 05795-31
3.0 mm I.D. x 100 mm 05796-21
3.0 mm I.D. x 150 mm 05797-11
3.0 mm I.D. x 250 mm 05798-01
4.6 mm I.D. x 30 mm 05879-41
4.6 mm I.D. x 50 mm 34451-21
4.6 mm I.D. x 100 mm 05799-91
4.6 mm I.D. x 150 mm 02486-71
4.6 mm I.D. x 250 mm 02485-81
6.0 mm I.D. x 150 mm 34419-61
6.0 mm I.D. x 250 mm 05800-41
10 mm I.D. x 50 mm 05801-31
10 mm I.D. x 150 mm 34466-41
10 mm I.D. x 250 mm 34376-21
20 mm I.D. x 150 mm 34476-11
20 mm I.D. x 250 mm 34373-51
28 mm I.D. x 250 mm 34456-71

 

Preparative Column (Particle Size : 15 µm) COSMOSIL 15C18-PAQ

Product Name Size Product No.
COSMOSIL 15C18-PAQ Guard Column
28 mm l.D. x 50 mm 05887-31
50 mm l.D. x 50 mm 05889-11
COSMOSIL 15C18-PAQ Packed Column
28 mm l.D. x 250 mm 05888-21
50 mm l.D. x 250 mm 05890-71
50 mm l.D. x 500 mm 05891-61

 

Protein Separation Columns (Wide Pore Columns)

1. COSMOGEL IEX Series

  • Available in 3 different ion-exchange modes 
    (Anion-exchange type, Cation-exchange type, Amphoteric ion-exchange type)
  • Available for 3 different application areas 
    (for Purification, for Ultra-fast analysis, for Precise analysis)
  • For separation of biopolymers such as proteins or nucleic acids?
Ion Exchange Mode Product Name Application Size
I.D. x Length (mm)
Product Number
Anion-exchange Type COSMOGEL IEX
Type Q
For Purification 4.6 x 50 06266-31
COSMOGEL IEX
Type Q-N
For Ultra-fast Analysis 4.6 x 30 06264-51
COSMOGEL IEX
Type Q-N
For Precise Analysis 4.6 x 100 06258-41
Cation-exchange Type COSMOGEL IEX
Type S
For Purification 4.6 × 50 06252-01
COSMOGEL IEX
Type S-N
For Ultra-fast Analysis 4.6 x 30 06251-11
COSMOGEL IEX
Type S-N
For Precise Analysis 4.6 × 100 06250-21
Amphoteric ion-exchange type COSMOGEL IEX
Type M
For Purification 4.6 x 50 06248-71
COSMOGEL IEX
Type M-N
For Precise Analysis 4.6 x 100 06244-11

 

2. COSMOSIL Protein-R

  • Excellent separation
  • High recovery rate
  • Outstanding stability at low pH
Product Name Size Product No.
COSMOSIL Protein-R Guard Column
4.6 mm l.D. x 10 mm 06518-31
10 mm l.D. x 20 mm 06528-01
COSMOSIL Protein-R Packed Column
2.0 mm l.D. x 150 mm 06514-71
4.6 mm l.D. x 50 mm 06525-31
4.6 mm l.D. x 150 mm 06526-21
4.6 mm l.D. x 250 mm 06527-11
10 mm l.D. x 150 mm 06529-91
10 mm l.D. x 250 mm 06530-51
20 mm l.D. x 150 mm 06531-41
20 mm l.D. x 250 mm 06532-31

 

3. COSMOSIL Diol-120-II, Diol-300-II, Diol-1000-II

  • Separate large hydrophilic molecules, such as proteins, polysaccharides and nucleic acids, by molecular size
  • Reduce undesirable adsorption
  • High pressure tolerance with silica gel-based packing material
  • Different products cover a wide range of molecular weight

COSMOSIL 5Diol-120-II

Product Name Size Product No.
COSMOSIL 5Diol-120-II Guard Column
7.5 mm l.D. x 50 mm 38049-91
COSMOSIL 5Diol-120-II Packed Column
7.5 mm l.D. x 300 mm 38050-51
7.5 mm l.D. x 600 mm 38051-41

COSMOSIL 5Diol-300-II

Product Name Size Product No.
COSMOSIL 5Diol-300-II Guard Column
7.5 mm l.D. x 50 mm 38052-31
COSMOSIL 5Diol-300-II Packed Column
7.5 mm l.D. x 300 mm 38053-21
7.5 mm l.D. x 600 mm 38054-11

COSMOSIL 5Diol-1000-II

Product Name Size Product No.
COSMOSIL 5Diol-1000-II Guard Column
7.5 mm l.D. x 50 mm 13337-81
COSMOSIL 5Diol-1000-II Packed Column
7.5 mm l.D. x 300 mm 13338-71