Polyplus-transfection® SA is a biotechnology company that develops and sells innovative solutions for the delivery of nucleic acids in research, bioproduction and therapeutics. Located close to the University of Strasbourg in Eastern France, Polyplus-transfection® is ISO 9001-certified since 2002 and supplies its wide range of reagents for the transfection of genes, oligonucleotides and siRNA through a worldwide distributor network.
Polyplus-transfection® reagents are involved in a growing number of clinical trials worldwide. In addition, Polyplus-transfection® holds a broad estate of patents and licenses including original methods for therapeutic siRNA delivery.
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Products |
Delivered Molecules |
Cell types |
Recommended use |
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Plasmid DNA |
Oligo-nucleotides (siRNA, miRNA & others) |
mRNA |
Proteins, peptides & antibodies |
Adherent |
Suspension |
Specific |
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|
In vitro |
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| ✓ | ✓ |
+++ |
Research purpose |
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| ✓ |
+++ |
+++ |
RNA interference |
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| ✓ |
+++ |
+++ |
Hard to transfect cells |
Research purpose |
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| ✓ |
+++ |
Suspension CHO & HEK-293 |
Bioproduction |
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| ✓ |
++ |
++ |
HEK-293 |
Virus & protein bioproduction |
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| ✓ |
++ |
++ |
HEK-293 |
Production of clinical batches of proteins and viruses |
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| ✓ |
++ |
+ |
High Throughput Screening Research purpose |
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| ✓ |
+++ |
Primary macrophages, glial & dendritic cells |
Cell specific |
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| ✓ |
+++ |
Primary Hepatocytes |
Cell specific |
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| ✓ |
+++ |
Endothelial cells |
Cell specific |
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|
+++ |
+++ |
Proteofection |
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Products |
Plasmid DNA |
Oligo-nucleotides |
mRNA |
Proteins |
Adherent |
Suspension |
Specific |
Recommended use |
|
In vivo |
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| ✓ | ✓ | ✓ |
in vivo delivery to all organs |
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| ✓ | ✓ | ✓ |
Therapeutic in vivo delivery to all organs |
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| ✓ | ✓ | ✓ |
Therapeutic in vivo delivery to all organs |
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| ✓ | ✓ | ✓ |
in vivo delivery delivery to mannose-receptor expressing tissue |
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| ✓ | ✓ | ✓ |
in vivo delivery to liver |
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| ✓ |
siRNA delivery to brain |
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|
Products |
Plasmid DNA |
Oligo-nucleotides |
mRNA |
Proteins |
Adherent |
Suspension |
Specific |
Recommended use |
|
Other |
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Molecular Biology & Diagnostics |
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Therapeutic siRNA |
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Therapeutic cationic Oligonucleotides |
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Transfection optimization |
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in vitro transfection, therapeutics |
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